Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 8/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952589 | 0.75 | MAP4K4 (0.46) | L3MBTL1RXRA | |
| SCHEMBL100969 | 0.73 | HCAR3 (0.56) | MAPTHCAR3HCAR2ALDH1A1CYP1A2 | |
| SCHEMBL30043919 | 0.73 | HCAR3 (0.56) | MAPTHCAR3HCAR2ALDH1A1CYP1A2 | |
| SCHEMBL29488316 | 0.73 | L3MBTL1 (1.00) | L3MBTL1MAPTALDH1A1POLBMAPK1 | |
| SCHEMBL27866226 | 0.73 | HCAR3 (0.49) | L3MBTL1MAPTHCAR3HCAR2ALDH1A1 | |
| SCHEMBL458559 | 0.73 | L3MBTL1 (1.00) | L3MBTL1MAPTALDH1A1POLBMAPK1 | |
| SCHEMBL14967355 | 0.72 | GCK (0.48) | RXRAMAPTHCAR3HCAR2POLB | |
| SCHEMBL25754457 | 0.71 | HCAR3 (0.58) | MAPTHCAR3HCAR2ALDH1A1CYP1A2 | |
| SCHEMBL28231895 | 0.71 | HCAR3 (0.53) | MAPTHCAR3HCAR2ALDH1A1CYP1A2 | |
| SCHEMBL27688524 | 0.71 | HCAR3 (0.57) | MAPTHCAR3HCAR2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-B1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2015-11-04 | — | — | EP | disclosed |