Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17220999 | 1.00 | NFE2L2 (0.46) | NFE2L2PDK2TRPA1MEN1KMT2A | |
| SCHEMBL17221007 | 0.82 | TUBB4A (0.41) | NFE2L2PDK2KMT2A | |
| SCHEMBL17220956 | 0.82 | APP (0.42) | NFE2L2PDK2TRPA1MEN1KMT2A | |
| SCHEMBL17220963 | 0.82 | TUBB4A (0.41) | NFE2L2PDK2TRPA1MEN1KMT2A | |
| SCHEMBL17220957 | 0.82 | CYP19A1 (0.42) | NFE2L2PDK2MEN1KMT2AGRM4 | |
| SCHEMBL17220954 | 0.82 | APP (0.42) | NFE2L2PDK2TRPA1MEN1KMT2A | |
| SCHEMBL17220967 | 0.82 | TUBB4A (0.41) | NFE2L2PDK2TRPA1MEN1KMT2A | |
| SCHEMBL17221011 | 0.82 | TUBB4A (0.41) | NFE2L2PDK2KMT2A | |
| SCHEMBL17220959 | 0.82 | CYP19A1 (0.42) | NFE2L2PDK2MEN1KMT2AGRM4 | |
| SCHEMBL17220982 | 0.79 | CYP1A1 (0.55) | NFE2L2PDK2TRPA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005936-B2 | Photoactive bioadhesive compositions | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2018-06-26 | — | — | US | claimed |
| US-20150315434-A1 | New Photoactive Bioadhesive Compositions | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-11-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005936-B2 | Photoactive bioadhesive compositions | L1CAM, CDH1, PCNA | NFE2L2 2120/4885PDK2 3340/4885TRPA1 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.