SCHEMBL1722101

SCHEMBL1722101

Nc1cc(I)cnc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29657163 0.75
SCHEMBL29960628 0.75
SCHEMBL29450123 0.75
SCHEMBL73289 0.75
SCHEMBL712724 0.75
SCHEMBL7353278 0.75
SCHEMBL652439 0.75
SCHEMBL8127902 0.74 ALDH1A1 (0.34)
SCHEMBL4881353 0.71
SCHEMBL10305653 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998271-A Pyridone compound and preparation method and application thereof 深圳信立泰药业股份有限公司 2025-05-13 CN disclosed
WO-2025067126-A1 PYRIDONE COMPOUNDS AND PREPARATION METHOD THEREFOR, AND APPLICATION 深圳信立泰药业股份有限公司 2025-04-03 WO disclosed
WO-2024220889-A1 STING AGONIST COMPOUNDS AND CONJUGATES THEREOF SEAGEN INC. (US) 2024-10-24 WO disclosed
US-11129814-B2 Antimicrobial agents TAXIS PHARMACEUTICALS, INC. (US) 2021-09-28 US disclosed
EP-2917212-B1 ANTIMICROBIAL AGENTS UNIV RUTGERS (US) 2019-06-12 EP disclosed
US-20180179225-A1 ANTIMICROBIAL AGENTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2018-06-28 US disclosed
US-20180179225-A1 ANTIMICROBIAL AGENTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2018-06-28 US disclosed
US-20160367531-A1 ANTIMICROBIAL AGENTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-12-22 US disclosed
US-20160367531-A1 ANTIMICROBIAL AGENTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-12-22 US disclosed
US-9458150-B2 Antimicrobial agents RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-10-04 US disclosed
EP-2494975-A1 Compounds and methods for promoting smoking cessation Research Triangle Institute (US) 2012-09-05 EP disclosed
EP-2404923-A1 7-azabicyclo[2.2.1]heptane derivatives useful for promoting smoking cessation RESEARCH TRIANGLE INSTITUTE (US) 2012-01-11 EP disclosed
US-20090318490-A1 COMPOUNDS AND METHODS FOR PROMOTING SMOKING CESSATION RESEARCH TRIANGLE INSITUTE (US) 2009-12-24 US disclosed
US-7615567-B2 Compounds and methods for promoting smoking cessation RESEARCH TRIANGLE INSTITUTE (US) 2009-11-10 US disclosed
US-20060069111-A1 Compounds and methods for promoting smoking cessation RESEARCH TRIANGLE INSITUTE (US) 2006-03-30 US disclosed
EP-1351684-A4 COMPOUNDS AND METHODS FOR PROMOTING SMOKING CESSATION RES TRIANGLE INST (US) 2005-01-19 EP disclosed
EP-1351684-A2 COMPOUNDS AND METHODS FOR PROMOTING SMOKING CESSATION Research Triangle Institute (US) 2003-10-15 EP disclosed
US-20030176434-A1 Compounds and methods for promoting smoking cessation RESEARCH TRIANGLE INSITUTE 2003-09-18 US disclosed
US-6538010-B1 Compounds may be used to treat a variety of other conditions and disease states and reagents for preventing smoking addiction. The present invention also relates to methods and reagents for treating nicotine addiction. RESEARCH TRIANGLE INSTITUTE 2003-03-25 US disclosed
WO-2002037927-A2 COMPOUNDS AND METHODS FOR PROMOTING SMOKING CESSATION RESEARCH TRIANGLE INSTITUTE (US) 2002-05-16 WO disclosed