SCHEMBL1722103

SCHEMBL1722103

O=C(OCc1ccccc1)SCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 8/20 0.65
ALDH1A1 P00352 4/20 0.55
TDP1 Q9NUW8 2/20 0.53
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
KMT2A Q03164 1/20 0.53
LMNA P02545 2/20 0.49
HCAR2 Q8TDS4 1/20 0.49
NOS3 P29474 1/20 0.47
NOS1 P29475 1/20 0.47
NOS2 P35228 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20644432 0.84 KMT2A (0.58) IDO1ALDH1A1TDP1L3MBTL1KMT2A
SCHEMBL10066809 0.83 IDO1 (0.63) IDO1ALDH1A1TDP1MAPK1L3MBTL1
SCHEMBL19473645 0.83 IDO1 (0.63) IDO1ALDH1A1L3MBTL1KMT2ANOS3
SCHEMBL24678431 0.83 ALDH1A1 (0.58) IDO1ALDH1A1TDP1MAPK1L3MBTL1
SCHEMBL16348281 0.83 ALDH1A1 (0.53) IDO1ALDH1A1TDP1MAPK1L3MBTL1
SCHEMBL30311836 0.82 ALDH1A1 (0.61) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL7081788 0.82 IDO1 (0.61) IDO1TDP1L3MBTL1NOS3NOS1
SCHEMBL9646712 0.82 ALDH1A1 (0.61) ALDH1A1TDP1MAPK1L3MBTL1SLC6A2
SCHEMBL8345818 0.81 IDO1 (0.50) IDO1ALDH1A1TDP1L3MBTL1KMT2A
SCHEMBL8310153 0.80 ALDH1A1 (0.55) IDO1ALDH1A1TDP1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114765987-B Heat and UV curable adhesive composition 汉高股份有限及两合公司 2025-01-24 CN disclosed
US-20240376133-A9 CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-11-14 US disclosed
EP-4396354-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2024-07-10 EP disclosed
WO-2024145435-A2 LIPID COMPOSITIONS AND METHODS FOR DELIVERY TO IMMUNE CELLS Life Technologies Corporation (US) 2024-07-04 WO disclosed
WO-2024130217-A1 STAPLED PEPTIDES AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2024-06-20 WO disclosed
WO-2024130218-A1 STAPLED PEPTIDES AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2024-06-20 WO disclosed
EP-4355350-A1 STAPLED PEPTIDES AND METHODS THEREOF Fog Pharmaceuticals, Inc. (US) 2024-04-24 EP disclosed
US-20230416283-A1 CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-12-28 US disclosed
WO-2023250342-A2 CYCLOPROPENE PHOSPHORAMIDITES AND CONJUGATES THEREOF Quantum-Si Incorporated (US) 2023-12-28 WO disclosed
EP-4288110-A2 TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS Biohaven Therapeutics Ltd. (US) 2023-12-13 EP disclosed
WO-2018223056-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF WAVE LIFE SCIENCES LTD. (SG) 2018-12-06 WO disclosed
EP-3297675-A1 5-ALA DERIVATIVES AND USE THEREOF Université de Genève (CH) 2018-03-28 EP disclosed
WO-2016185368-A1 5-ALA DERIVATIVES AND USE THEREOF UNIVERSITE DE GENEVE (CH) 2016-11-24 WO disclosed
EP-2970184-A1 COMPOUNDS AND USES THEREOF FOR THE MODULATON OF HEMOGLOBIN Global Blood Therapeutics, Inc. (US) 2016-01-20 EP disclosed
EP-2958895-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF Kala Pharmaceuticals, Inc. (US) 2015-12-30 EP disclosed
WO-2014150261-A1 COMPOUNDS AND USES THEREOF FOR THE MODULATON OF HEMOGLOBIN GLOBAL BLOOD THERAPEUTICS, INC. (US) 2014-09-25 WO disclosed
WO-2014130612-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF KALA PHARMACEUTICALS, INC. (US) 2014-08-28 WO disclosed
EP-2404912-A2 Process and intermediates for the preparation of antitumoral dihydropyran-2-one compounds Pharma Mar S.A. (ES) 2012-01-11 EP disclosed
EP-1951656-A1 HISTONE DEACETYLASE INHIBITORS AS THERAPEUTICS FOR NEUROLOGICAL DISEASES The Scripps Research Institute (US) 2008-08-06 EP disclosed
WO-2007058927-A1 HISTONE DEACETYLASE INHIBITORS AS THERAPEUTICS FOR NEUROLOGICAL DISEASES THE SCRIPPS RESEARCH INSTITUTE (US) 2007-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376133-A9 CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS PGD, CDCA2, MCM2 IDO1 530/4885ALDH1A1 625/4885TDP1 87/4885
US-20230416283-A1 CROSSLINKING COMONOMERS FOR HIGH PERFORMANCE DEGRADABLE THERMOSETS PGD, CDCA2, MCM2 IDO1 530/4885ALDH1A1 625/4885TDP1 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.