Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117700 | 0.84 | POLB (0.41) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL6586596 | 0.82 | MAPT (0.44) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27367126 | 0.79 | KMT2A (0.46) | CYP1A2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6770996 | 0.78 | ALDH1A1 (0.47) | KMT2AMEN1POLBALDH1A1PKM | |
| SCHEMBL27545836 | 0.78 | KMT2A (0.40) | CYP1A2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6585360 | 0.78 | TXNRD1 (0.39) | POLBALDH1A1MAPTG6PDTLR9 | |
| Hydrochloric Acid SCHEMBL6770644 | 0.77 | ALDH1A1 (0.46) | KMT2AMEN1POLBALDH1A1PKM | |
| SCHEMBL6589360 | 0.76 | TXNRD1 (0.49) | KMT2AMEN1POLBALDH1A1PKM | |
| SCHEMBL27545845 | 0.75 | KMT2A (0.37) | CYP1A2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL11412120 | 0.75 | CDK2 (0.57) | CYP1A2KMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015164956-A1 | BENZISOTHIAZOLE DERIVATIVE COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-11-05 | — | — | WO | disclosed |