Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27545836 | 0.89 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL27545845 | 0.81 | KMT2A (0.37) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6586596 | 0.81 | MAPT (0.44) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8117700 | 0.80 | POLB (0.41) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17224014 | 0.79 | CYP1A2 (0.48) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL27545851 | 0.78 | SMN1; SMN2 (0.35) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6585360 | 0.74 | TXNRD1 (0.39) | SMN1; SMN2ALDH1A1POLBLMNAHPGD | |
| SCHEMBL30999993 | 0.73 | DYRK1A (0.51) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL5343713 | 0.73 | ALDH1A1 (0.40) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6778003 | 0.72 | DYRK1A (0.45) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1055686-C | Substituted Benzisoxazole and benzisothiazole herbicidal agents | AMERICAN CYANAMID CO (US) | 2000-08-23 | — | — | CN | disclosed |
| CN-1136561-A | Substituted Benzisoxazole and benzisothiazole herbicidal agents | AMERICAN CYANAMID CO (US) | 1996-11-27 | — | — | CN | disclosed |