⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224242 | 1.00 | — | — | |
| SCHEMBL17292443 | 1.00 | — | — | |
| SCHEMBL17224241 | 1.00 | — | — | |
| SCHEMBL17236093 | 0.81 | CTSK (0.49) | — | |
| SCHEMBL17236152 | 0.78 | — | — | |
| SCHEMBL15939540 | 0.76 | DRD3 (0.39) | — | |
| SCHEMBL17292437 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL17224233 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL17305960 | 0.68 | DRD3 (0.31) | — | |
| SCHEMBL15404521 | 0.66 | EPHX2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137471-A1 | PROCESSES OF PREPARING A JAK1 INHIBITOR AND NEW FORMS THERETO | Incyte Corporation (US) | 2017-03-08 | — | — | EP | disclosed |
| WO-2015168246-A1 | PROCESSES OF PREPARING A JAK1 INHIBITOR AND NEW FORMS THERETO | INCYTE CORPORATION (US) | 2015-11-05 | — | — | WO | disclosed |