Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 3/20 | 0.39 |
| ▸ | FPR2 | P25090 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25C | P30307 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26054317 | 0.89 | TGM2 (0.48) | TGM2NPY4RFPR2KMT2AUSP2 | |
| SCHEMBL14566832 | 0.86 | FPR2 (0.43) | TGM2FPR2KMT2AUSP2MEN1 | |
| SCHEMBL17399557 | 0.85 | MEN1 (0.41) | TGM2FPR2KMT2AUSP2MEN1 | |
| SCHEMBL12119403 | 0.83 | TGM2 (0.61) | TGM2NPY4RFPR2KMT2AUSP2 | |
| Hydrochloric Acid SCHEMBL13737398 | 0.82 | TGM2 (0.60) | TGM2NPY4RFPR2KMT2AUSP2 | |
| SCHEMBL14192855 | 0.79 | ABCB1 (0.40) | TGM2FPR2KMT2AUSP2MEN1 | |
| SCHEMBL14559742 | 0.78 | MEN1 (0.44) | TGM2FPR2KMT2AUSP2MEN1 | |
| SCHEMBL26058245 | 0.78 | TGM2 (0.48) | TGM2NPY4RFPR2KMT2AUSP2 | |
| SCHEMBL18732965 | 0.77 | TGM2 (0.50) | TGM2NPY4RFPR2KMT2AUSP2 | |
| SCHEMBL18087519 | 0.75 | TGM2 (0.62) | TGM2NPY4RFPR2KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137554-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | Ecole Normale Superieure De Lyon (FR) | 2017-03-08 | — | — | EP | disclosed |
| WO-2015166295-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2015-11-05 | — | — | WO | disclosed |