Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28069700 | 0.79 | GGT1 (0.41) | GGT1GABRR1CPB2CPB1PAOX | |
| SCHEMBL1665173 | 0.75 | CA12 (0.48) | TSHR | |
| Acetic Acid SCHEMBL5087420 | 0.72 | GABRR1 (0.43) | GGT1GABRR1CPB2CPB1PAOX | |
| Acetic Acid SCHEMBL8775545 | 0.72 | GABRR1 (0.43) | GGT1GABRR1CPB2CPB1PAOX | |
| SCHEMBL24503897 | 0.71 | GGT1 (0.43) | GGT1GABRR1CPB2CPB1PAOX | |
| Acetic Acid SCHEMBL10524376 | 0.71 | GABRR1 (0.41) | GGT1GABRR1CPB2CPB1PAOX | |
| SCHEMBL28081085 | 0.71 | GGT1 (0.56) | GGT1GABRR1CPB2CPB1 | |
| Acetic Acid SCHEMBL28168812 | 0.71 | GABRR1 (0.41) | GGT1GABRR1CPB2CPB1PAOX | |
| Acetic Acid SCHEMBL6712974 | 0.71 | GGT1 (0.39) | GGT1GABRR1CPB2CPB1PAOX | |
| Acetic Acid SCHEMBL29012712 | 0.71 | GABRR1 (0.41) | GGT1GABRR1CPB2CPB1PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137485-A1 | CHELATOR MODIFIED MAGNETIC SILICA NANOPARTICLES, THEIR USE AND PREPARATION | Universidade de Aveiro (PT) | 2017-03-08 | — | — | EP | claimed |
| WO-2015166415-A1 | CHELATOR MODIFIED MAGNETIC SILICA NANOPARTICLES, THEIR USE AND PREPARATION | UNIVERSIDADE DE AVEIRO (PT) | 2015-11-05 | — | — | WO | claimed |
| EP-3137485-A1 | CHELATOR MODIFIED MAGNETIC SILICA NANOPARTICLES, THEIR USE AND PREPARATION | Universidade de Aveiro (PT) | 2017-03-08 | — | — | EP | disclosed |
| WO-2015166415-A1 | CHELATOR MODIFIED MAGNETIC SILICA NANOPARTICLES, THEIR USE AND PREPARATION | UNIVERSIDADE DE AVEIRO (PT) | 2015-11-05 | — | — | WO | disclosed |