Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 3/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043378 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL7516558 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL2315211 | 0.73 | ALDH1A1 (0.42) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL9483954 | 0.72 | ALDH1A1 (0.46) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL21647263 | 0.72 | ALDH1A1 (0.46) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL27902708 | 0.71 | CYP2C19 (0.44) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL108616 | 0.70 | ALDH1A1 (0.43) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL1414703 | 0.70 | ALDH1A1 (0.43) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL28390182 | 0.70 | ALDH1A1 (0.43) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL5809750 | 0.69 | ALDH1A1 (0.42) | ALDH1A1CYP2D6TSHRCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021437-A1 | IMPROVING, MAINTAINING, PROTECTING AND REPAIRING TISSUE INTEGRITY, BARRIER FUNCTION AND IMMUNITY USING A COMPOSITION COMPRISING A SOURCE OF ZINC IONS | Colgate-Palmolive Company (US) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021203132-A1 | IMPROVING, MAINTAINING, PROTECTING AND REPAIRING TISSUE INTEGRITY, BARRIER FUNCTION AND IMMUNITY USING A COMPOSITION COMPRISING A SOURCE OF ZINC IONS | COLGATE-PALMOLIVE COMPANY (US) | 2021-10-07 | — | — | WO | disclosed |
| US-20210308028-A1 | Compositions and Methods for Maintaining and Protecting Tissue Integrity and Barrier Function | COLGATE-PALMOLIVE COMPANY (US) | 2021-10-07 | — | — | US | disclosed |
| EP-3137040-A1 | ORAL CARE COMPOSITION CONTAINING SILICA AND ZINC CITRATE | Colgate-Palmolive Company (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20170049671-A1 | Oral Care Composition Containing Silica and Zinc Citrate | COLGATE PALMOLIVE CO (US) | 2017-02-23 | — | — | US | disclosed |
| WO-2015167488-A1 | ORAL CARE COMPOSITION CONTAINING SILICA AND ZINC CITRATE | COLGATE-PALMOLIVE COMPANY (US) | 2015-11-05 | — | — | WO | disclosed |