SCHEMBL2315211

SCHEMBL2315211

O=C(O)CC(CC(=O)O)(OO)C(=O)O.[Zn]

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
HMGCR P04035 1/20 0.36
CHRM1 P11229 1/20 0.36
TBXA2R P21731 1/20 0.36
ADRA1A P35348 1/20 0.36
ACLY P53396 3/20 0.34
CPT2 P23786 2/20 0.33
KDM4E B2RXH2 1/20 0.31
FFAR1 O14842 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108616 0.97 ALDH1A1 (0.43) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL337214 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL11021067 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL2487792 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL2966015 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL988732 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL4118128 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL28505954 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
Water SCHEMBL2959958 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL336806 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070031526-A1 Topical Deodorant Compositions Based on Hydroxycitric Acid BIODERM RESEARCH (US) 2007-02-08 US claimed
EP-2538917-B1 COMPOSITION CONTAINING EXTRACT OF VENUS FLYTRAP FOR COSMETIC TREATMENT QUANTUM PHARMACEUTICALS LTD (CN) 2016-11-16 EP disclosed
US-20140308222-A1 COMPOSITION CONTAINING EXTRACT OF VENUS FLYTRAP FOR COSMETIC TREATMENT QUANTUM PHARMACEUTICALS LTD. (CN) 2014-10-16 US disclosed
US-20130202541-A1 COMPOSITION CONTAINING EXTRACT OF VENUS FLYTRAP FOR COSMETIC TREATMENT ROYAL GOVERNMENT OF BHUTAN, MINISTRY OF AGRICULTURE (BT) 2013-08-08 US disclosed
EP-2538917-A1 COMPOSITION CONTAINING EXTRACT OF VENUS FLYTRAP FOR COSMETIC TREATMENT Quantum Pharmaceuticals Ltd. (CN) 2013-01-02 EP disclosed
WO-2011093769-A1 COMPOSITION CONTAINING EXTRACT OF VENUS FLYTRAP FOR COSMETIC TREATMENT QUANTUM PHARMACEUTICALS LTD. ET AL. (CN) 2011-08-04 WO disclosed
US-7615546-B2 Skin disorders; acne; alopecia BIODERM RESEARCH (US) 2009-11-10 US disclosed
US-20090130154-A1 Topical Delivery of Biological and Cosmetic Agents by Zeolites BIODERM RESEARCH (US) 2009-05-21 US disclosed
US-20090042846-A1 Topical Delivery System for Phytosterols BIODERM RESEARCH (US) 2009-02-12 US disclosed
US-20080139507-A1 Method of Treating Skin Condition Including Acne, Skin Aging, Body Odor & Diaper Rash by Zinc Zeolite Clathrates BIODERM RESEARCH (US) 2008-06-12 US disclosed
US-20070041924-A1 Sebum Control Compositions Based on Saponins and Sapogenins BIODERM RESEARCH (US) 2007-02-22 US disclosed
US-20070031526-A1 Topical Deodorant Compositions Based on Hydroxycitric Acid BIODERM RESEARCH (US) 2007-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090042846-A1 Topical Delivery System for Phytosterols COL14A1, CYP27A1, CYP46A1 ALDH1A1 1167/4885CYP2D6 1787/4885TSHR 902/4885
US-20090130154-A1 Topical Delivery of Biological and Cosmetic Agents by Zeolites TYR, MMP1, MMP17 ALDH1A1 1967/4885CYP2D6 3118/4885TSHR 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.