Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PARG | Q86W56 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSC | P53634 | 2/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835393 | 1.00 | KDM4E (0.56) | KDM4ERECQLSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2225334 | 0.91 | KDM4E (0.67) | KDM4ERECQLSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8355420 | 0.91 | KDM4E (0.67) | KDM4ERECQLSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1723222 | 0.90 | UCHL1 (0.54) | KDM4ERECQLSMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL15687975 | 0.89 | KDM4E (0.64) | KDM4ERECQLSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11372059 | 0.86 | LMNA (0.56) | KDM4ERECQLSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2192046 | 0.83 | KDM4E (0.54) | KDM4ERECQLSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2192047 | 0.83 | KDM4E (0.54) | KDM4ERECQLSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4041413 | 0.83 | KDM4E (0.74) | KDM4ERECQLSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7648169 | 0.83 | KDM4E (0.81) | KDM4ERECQLSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344449-A1 | ARYL-PHENYL-SULFONAMIDO-CYCLOALKYL COMPOUNDS AND THEIR USE | Pimco 2664 Limited (GB) | 2011-07-20 | — | — | EP | disclosed |