Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.56 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.56 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.56 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149664 | 0.87 | PRSS1 (0.73) | ALDH1A1LMNASMN1; SMN2MAPK1PRSS1 | |
| SCHEMBL30576720 | 0.86 | PRSS1 (0.71) | ALDH1A1LMNASMN1; SMN2MAPK1PRSS1 | |
| SCHEMBL31550495 | 0.85 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2MAPK1PRSS1 | |
| SCHEMBL13073338 | 0.84 | LMNA (0.59) | ALDH1A1LMNASMN1; SMN2MAPK1PRSS1 | |
| SCHEMBL30440860 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2MAPK1PRSS1 | |
| SCHEMBL8426731 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2MAPK1PRSS1 | |
| SCHEMBL8178335 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2MAPK1PRSS1 | |
| SCHEMBL8323868 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2MAPK1PRSS1 | |
| SCHEMBL504661 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2MAPK1PRSS1 | |
| SCHEMBL5873775 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2MAPK1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| EP-2403835-A1 | NOVEL PHENYL IMIDAZOLES AND PHENYL TRIAZOLES AS GAMMA-SECRETASE MODULATORS | Pfizer Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100606-A1 | NOVEL PHENYL IMIDAZOLES AND PHENYL TRIAZOLES AS GAMMA-SECRETASE MODULATORS | PFIZER INC. (US) | 2010-09-10 | — | — | WO | disclosed |