Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.56 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.56 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.56 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126514 | 0.97 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL19328790 | 0.86 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL31550495 | 0.85 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL27777087 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL8156969 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL21771367 | 0.84 | LMNA (0.59) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL16258192 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL17079191 | 0.84 | HTT (0.64) | LMNASMN1; SMN2PRSS1TPSAB1HTT | |
| SCHEMBL13644307 | 0.84 | LMNA (0.58) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL8426731 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438160-A | Carbamoyl compounds for the treatment of viral infections | 豪夫迈·罗氏有限公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022043374-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-03-03 | — | — | WO | disclosed |
| CN-108794353-B | Application of compound as blocking reagent of glycosyl on antibody | 嵊州宝康医疗科技有限公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-108794353-B | Application of compound as blocking reagent of glycosyl on antibody | 嵊州宝康医疗科技有限公司 | 2021-08-03 | — | — | CN | disclosed |
| US-8865755-B2 | Dual-acting antihypertensive agents | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2014-10-21 | — | — | US | disclosed |
| US-20130210874-A1 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| WO-2013093931-A2 | NOVEL PRODRUGS OF PHENOLIC DRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013093931-A2 | NOVEL PRODRUGS OF PHENOLIC DRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2013-06-27 | — | — | WO | disclosed |
| US-8338418-B2 | Dual-acting antihypertensive agents | THERAVANCE, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100022599-A1 | imidazole or triazole derivatives such as 4-[4-((R)-1-Benzyl-2-hydroxycarbamoylethylcarbamoyl)-2-butylimidazol-1-ylmethyl]benzoic acid methyl ester, used for treating congestive heart failure or as hypotensive agents | THERAVANCE BIOPHARMA R&D IP, LLC | 2010-01-28 | — | — | US | disclosed |
| US-7618983-B2 | Bicyclic triazole α4 integrin inhibitors | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-11-17 | — | — | US | disclosed |
| US-20060128748-A1 | Bicyclic triazole alpha4 integrin inhibitors | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-06-15 | — | — | US | disclosed |
| WO-2006052962-A2 | BICYCLIC TRIAZOLE A4 INTEGRIN INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-18 | — | — | WO | disclosed |
| EP-0076557-B1 | PEPTIDES AND PSEUDOPEPTIDES IN WHICH THE N TERMINUS BEARS TWO SUBSTITUENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-13 | — | — | EP | disclosed |
| US-4464300-A | PSYCHOTROPIC, ANXIOLYTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1984-08-07 | — | — | US | disclosed |
| US-4421744-A | OPIATE RECEPTOR ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-12-20 | — | — | US | disclosed |
| EP-0076557-A2 | Peptides and pseudopeptides in which the N terminus bears two substituents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-04-13 | — | — | EP | disclosed |
| US-4341704-A | 4,1-Benzoxazepines and thia analogs thereof | SHIONOGI & CO., LTD. (JP) | 1982-07-27 | — | — | US | disclosed |
| US-4297280-A | USEFUL AS CENTRAL NERVOUS SYSTEM DRUGS | SHIONOGI & CO., LTD. (JP) | 1981-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210874-A1 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS | AGTR1, REN, AGTR2 | ALDH1A1 2758/4885LMNA 1515/4885SMN1; SMN2 4276/4885 |
| US-20100022599-A1 | imidazole or triazole derivatives such as 4-[4-((R)-1-Benzyl-2-hydroxycarbamoylethylcarbamoyl)-2-butylimidazol-1-ylmethyl]benzoic acid methyl ester, used for treating congestive heart failure or as hypotensive agents | AGTR1, REN, AGTR2 | ALDH1A1 2509/4885LMNA 1794/4885SMN1; SMN2 3885/4885 |
| US-20060128748-A1 | Bicyclic triazole alpha4 integrin inhibitors | ITGA4, ITGB4, ITGB5 | ALDH1A1 1568/4885LMNA 3900/4885SMN1; SMN2 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.