Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13314382 | 1.00 | TGM2 (0.56) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL12712296 | 0.85 | TGM2 (0.63) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL13348927 | 0.82 | TGM2 (0.59) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL13055383 | 0.80 | LMNA (0.80) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL19120695 | 0.79 | HSD17B10 (0.47) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL966270 | 0.78 | LMNA (0.63) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL30697760 | 0.78 | TGM2 (0.86) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL26630558 | 0.78 | LMNA (0.63) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL19750475 | 0.78 | LMNA (0.63) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL8247523 | 0.78 | LMNA (0.63) | TGM2LMNASMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170198283-A1 | TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES | NUEVOLUTION A/S (DK) | 2017-07-13 | — | — | US | disclosed |
| US-9688980-B2 | Templated molecules and methods for using such molecules | NUEVOLUTION (DK) | 2017-06-27 | — | — | US | disclosed |
| US-20150315567-A1 | TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES | NUEVOLUTION A/S (DK) | 2015-11-05 | — | — | US | disclosed |