Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12712296 | 0.87 | TGM2 (0.63) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL13055383 | 0.82 | LMNA (0.80) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL17227877 | 0.82 | TGM2 (0.56) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL13314382 | 0.82 | TGM2 (0.56) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL15216787 | 0.81 | SMN1; SMN2 (0.56) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL30697760 | 0.80 | TGM2 (0.86) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL13594188 | 0.80 | ALDH1A1 (0.69) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL733157 | 0.79 | LMNA (0.71) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10243339 | 0.79 | LMNA (0.71) | TGM2LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL7364819 | 0.79 | LMNA (0.65) | TGM2LMNASMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8932992-B2 | Templated molecules and methods for using such molecules | NUEVOLUTION A/S (DK) | 2015-01-13 | — | — | US | disclosed |
| US-7727713-B2 | Templated molecules and methods for using such molecules | NUEVOLUTION A/S (DK) | 2010-06-01 | — | — | US | disclosed |