Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17103196 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPTPKMTDP1LMNA | |
| SCHEMBL17228270 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MAPTPKMTDP1KCNMA1 | |
| SCHEMBL17122561 | 0.88 | KMT2A (0.55) | ALDH1A1MAPTPKMTDP1KCNMA1 | |
| SCHEMBL17103173 | 0.86 | MEN1 (0.53) | ALDH1A1MAPTPKMTDP1KCNMA1 | |
| SCHEMBL29430118 | 0.86 | MEN1 (0.53) | ALDH1A1MAPTPKMTDP1KCNMA1 | |
| Hydrochloric Acid SCHEMBL17103200 | 0.85 | MEN1 (0.52) | ALDH1A1MAPTPKMTDP1KCNMA1 | |
| Sulfuric Acid SCHEMBL17103341 | 0.83 | KMT2A (0.52) | ALDH1A1MAPTPKMTDP1KMT2A | |
| Sulfuric Acid SCHEMBL17103345 | 0.83 | KMT2A (0.52) | ALDH1A1MAPTPKMTDP1KMT2A | |
| SCHEMBL17103449 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTPKMTDP1KMT2A | |
| SCHEMBL21301505 | 0.77 | MAPT (0.49) | ALDH1A1MAPTLMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9402819-B2 | Anti-HIV compound and preparation method and use thereof | SICHUAN UNIVERSITY (CN) | 2016-08-02 | — | — | US | disclosed |
| US-20150313853-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN UNIVERSITY (CN) | 2015-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150313853-A1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | FURIN, CD4, SI | ALDH1A1 786/4885MAPT 3953/4885PKM 2187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.