Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL325537 | 0.91 | PROKR1 (0.39) | LMNAHPGDSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL1722509 | 0.89 | PROKR1 (0.47) | LMNAKMT2AHPGDALDH1A1 | |
| SCHEMBL1723221 | 0.87 | GRM5 (0.49) | LMNAKMT2AHPGDSMN1; SMN2HTT | |
| SCHEMBL327168 | 0.84 | LMNA (0.48) | LMNAKMT2AHPGDSMN1; SMN2HTT | |
| SCHEMBL303461 | 0.84 | LMNA (0.43) | LMNAKMT2AHPGDSMN1; SMN2HTT | |
| SCHEMBL1710991 | 0.84 | LMNA (0.47) | LMNAKMT2AHPGDSMN1; SMN2HTT | |
| SCHEMBL302109 | 0.83 | LMNA (0.47) | LMNAKMT2AHPGDSMN1; SMN2HTT | |
| SCHEMBL304021 | 0.83 | PROKR1 (0.49) | LMNAKMT2AHPGDSMN1; SMN2HTT | |
| SCHEMBL1722401 | 0.82 | KMT2A (0.55) | LMNAKMT2AHPGDSMN1; SMN2HTT | |
| SCHEMBL302862 | 0.81 | GRM5 (0.42) | LMNAKMT2AHPGDMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344456-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | Xention Limited (GB) | 2011-07-20 | — | — | EP | disclosed |