Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723248 | 0.86 | MEN1 (0.55) | MEN1KMT2APOLBLMNATRPM8 | |
| SCHEMBL3281840 | 0.83 | KMT2A (0.51) | MEN1KMT2ACNR1CNR2PTGES | |
| SCHEMBL1723280 | 0.83 | KMT2A (0.49) | MEN1KMT2APOLBCNR1CNR2 | |
| SCHEMBL1722397 | 0.80 | MEN1 (0.61) | MEN1KMT2APOLBLMNAPTGES | |
| SCHEMBL2211492 | 0.78 | MEN1 (0.53) | MEN1KMT2APOLBCNR1CNR2 | |
| SCHEMBL304444 | 0.77 | MAPT (0.43) | MEN1KMT2ACNR1CNR2LMNA | |
| SCHEMBL2774329 | 0.75 | TAS2R14 (0.74) | MEN1KMT2APOLBLMNAPTGES | |
| SCHEMBL1711098 | 0.75 | MEN1 (0.76) | MEN1KMT2APOLBCNR1CNR2 | |
| SCHEMBL18487096 | 0.74 | MEN1 (0.46) | MEN1KMT2APTGESALDH1A1KDM4E | |
| SCHEMBL2212915 | 0.74 | MEN1 (0.58) | MEN1KMT2ALMNAPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344456-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | Xention Limited (GB) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010023445-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | disclosed |