Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172345 | 0.87 | OXTR (0.51) | OXTRAVPR1AMEN1KMT2AMAPT | |
| SCHEMBL27658447 | 0.81 | OXTR (0.58) | OXTRAVPR1AMEN1KMT2AMAPT | |
| SCHEMBL23915663 | 0.80 | OXTR (0.61) | OXTRAVPR1AMEN1KMT2AMAPT | |
| SCHEMBL23545724 | 0.79 | HTT (0.57) | MEN1KMT2AHTTCYP3A4LMNA | |
| SCHEMBL12305651 | 0.77 | MEN1 (0.67) | OXTRAVPR1AMEN1KMT2AMAPT | |
| SCHEMBL17069247 | 0.77 | GABRA1 (0.63) | OXTRAVPR1AMEN1KMT2AMAPT | |
| SCHEMBL16791829 | 0.76 | OXTR (0.56) | OXTRAVPR1AMEN1KMT2AMAPT | |
| SCHEMBL20535909 | 0.76 | CYP2D6 (0.79) | KMT2AMAPTHIF1ACYP3A4CYP2C9 | |
| Acetic Acid SCHEMBL11588262 | 0.75 | CA2 (0.56) | OXTRAVPR1AMEN1KMT2AMAPT | |
| SCHEMBL18756245 | 0.75 | TSHR (0.67) | HIF1ACA12CA2CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |