Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18236733 | 0.82 | NAMPT (0.46) | LMNAMAPTMAPK1GAAALDH1A1 | |
| SCHEMBL24762812 | 0.81 | MEN1 (0.50) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL12923898 | 0.81 | MEN1 (0.50) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7992509 | 0.79 | GAA (0.42) | LMNAMAPTMAPK1GAAALDH1A1 | |
| SCHEMBL21799751 | 0.78 | ANPEP (0.50) | LMNAALDH1A1 | |
| SCHEMBL172622 | 0.78 | LMNA (0.63) | LMNAMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL2567878 | 0.77 | SLC2A4 (0.41) | LMNAMAPTMAPK1GAAALDH1A1 | |
| SCHEMBL1702982 | 0.77 | GAA (0.42) | LMNAMAPTMAPK1GAAALDH1A1 | |
| SCHEMBL211808 | 0.76 | GAA (0.49) | LMNAMAPTMAPK1GAAALDH1A1 | |
| SCHEMBL172355 | 0.75 | SLC6A4 (0.49) | MAPTGAAMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |