Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710874 | 0.81 | SLC6A4 (0.49) | SLC6A4GAAMEN1KMT2ACYP1A2 | |
| SCHEMBL13995738 | 0.81 | SLC6A4 (0.47) | SLC6A4GAAMEN1KMT2ACYP1A2 | |
| SCHEMBL21799751 | 0.79 | ANPEP (0.50) | CYP1A2 | |
| SCHEMBL172622 | 0.79 | LMNA (0.63) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24762812 | 0.78 | MEN1 (0.50) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL12923898 | 0.78 | MEN1 (0.50) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL14266763 | 0.77 | SLC6A4 (0.53) | SLC6A4GAAMEN1KMT2ACYP1A2 | |
| SCHEMBL24500864 | 0.76 | SLC6A4 (0.63) | SLC6A4MAOASLC6A2SLC6A3 | |
| SCHEMBL172367 | 0.75 | LMNA (0.44) | GAAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL172625 | 0.75 | LOXL2 (0.55) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |