Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660132 | 0.79 | DRD2 (0.44) | POLBMEN1KMT2ALMNAHTT | |
| SCHEMBL658984 | 0.78 | LMNA (0.39) | SMN1; SMN2MEN1KMT2ALMNATSHR | |
| SCHEMBL658763 | 0.76 | GAA (0.38) | SMN1; SMN2MEN1KMT2ALMNATSHR | |
| SCHEMBL659448 | 0.75 | AKR1C3 (0.38) | LMNAHTT | |
| SCHEMBL657755 | 0.74 | HSP90AA1 (0.32) | MEN1KMT2A | |
| SCHEMBL659176 | 0.74 | KCNA5 (0.36) | POLBMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL657987 | 0.74 | DRD2 (0.40) | POLBSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL660752 | 0.74 | DRD2 (0.34) | POLBMEN1KMT2ALMNAHTT | |
| SCHEMBL657655 | 0.71 | ALDH1A1 (0.46) | POLBMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL660336 | 0.68 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406243-B1 | BENZOFURAN DERIVATIVES | TAKEDA PHARMACEUTICAL (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2406243-A1 | BENZOFURAN DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010104194-A1 | BENZOFURAN DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | WO | disclosed |