SCHEMBL9525909

SCHEMBL9525909

CC(C)(C)c1ccc(CC(=O)Cc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 6/20 0.53
EPHX2 P34913 6/20 0.53
ESRRB O95718 1/20 0.51
ESRRG P62508 1/20 0.51
LMNA P02545 3/20 0.50
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
RXRG P48443 1/20 0.50
NLRP3 Q96P20 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HDAC3 O15379 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC1 Q13547 1/20 0.47
TYR P14679 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11398239 0.92 ALDH1A1 (0.59) NR1H4EPHX2ESRRGLMNARXRA
SCHEMBL15435394 0.90 NR1H4 (0.49) NR1H4EPHX2ESRRBESRRGLMNA
SCHEMBL5692683 0.88 ESRRG (0.50) NR1H4EPHX2ESRRBESRRGLMNA
SCHEMBL28788483 0.88 NR1H4 (0.47) NR1H4EPHX2ESRRBESRRGLMNA
SCHEMBL15435250 0.88 NR1H4 (0.47) NR1H4EPHX2ESRRBESRRGLMNA
SCHEMBL13090461 0.87 CYP2D6 (0.47) NR1H4EPHX2ESRRBESRRGLMNA
SCHEMBL17451337 0.87 MEN1 (0.61) NR1H4EPHX2LMNAMAPTSMN1; SMN2
SCHEMBL6942764 0.86 NR1H4 (0.46) NR1H4EPHX2ESRRBESRRGLMNA
SCHEMBL4689867 0.84 NR1H4 (0.51) NR1H4EPHX2ESRRBESRRGLMNA
SCHEMBL6566395 0.84 NR1H4 (0.51) NR1H4EPHX2ESRRBESRRGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260107628-A1 SYNTHESIS METHOD FOR HEXAPHENYLBENZENE-BASED ORGANIC SMALL MOLECULES AND APPLICATION IN ELECTROLUMINESCENT DEVICES TIANJIN UNIVERSITY (CN) 2026-04-16 US claimed
US-4448657-A USING OIL SOLUBLE PHOTOINITIATORS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1984-05-15 US claimed
US-20260107628-A1 SYNTHESIS METHOD FOR HEXAPHENYLBENZENE-BASED ORGANIC SMALL MOLECULES AND APPLICATION IN ELECTROLUMINESCENT DEVICES TIANJIN UNIVERSITY (CN) 2026-04-16 US disclosed
US-20220081378-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2022-03-17 US disclosed
US-11196006-B2 Organic compound and organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2021-12-07 US disclosed
US-20200111963-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2020-04-09 US disclosed
EP-2294038-B1 FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND CANON KK (JP) 2016-07-27 EP disclosed
US-9397298-B2 Organic compound, organic light-emitting device, and image display device CANON KABUSHIKI KAISHA (JP) 2016-07-19 US disclosed
US-9397298-B2 Organic compound, organic light-emitting device, and image display device CANON KABUSHIKI KAISHA (JP) 2016-07-19 US disclosed
US-9005778-B2 Organic compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2015-04-14 US disclosed
US-9005778-B2 Organic compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2015-04-14 US disclosed
EP-0259972-A2 Heterocyclic propene amide derivatives, processes for their preparation and their use as pharmaceuticals LILLY INDUSTRIES LIMITED (GB) 1988-03-16 EP disclosed
US-4448657-A USING OIL SOLUBLE PHOTOINITIATORS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1984-05-15 US disclosed
US-4260760-A BACTERICIDES, ALGICIDES MERCK & CO., INC. (US) 1981-04-07 US disclosed
US-4172094-A Polyamine compounds MERCK & CO., INC. (US) 1979-10-23 US disclosed
US-4111873-A DITHIO COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1978-09-05 US disclosed
US-4079059-A ANTIMICROBIAL, ALGAE INHIBITORS MERCK & CO., INC. (US) 1978-03-14 US disclosed
US-4070400-A MICROBIOCIDES, ALGICIDES MERCK & CO., INC. (US) 1978-01-24 US disclosed
US-4061775-A Polyamine compounds as antibacterial agents MERCK & CO., INC. (US) 1977-12-06 US disclosed
US-4058624-A Broad spectrum antibacterial compositions containing tris (hydroxymethyl)-aminomethane and diphenyl and loweralkyl substituted diphenyl polyamines MERCK & CO., INC. (US) 1977-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11196006-B2 Organic compound and organic light-emitting element CRY1, CRY2, NR2E3 NR1H4 366/4885EPHX2 3301/4885ESRRB 604/4885
US-20200111963-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CRY1, CRY2, NR2E3 NR1H4 366/4885EPHX2 3301/4885ESRRB 604/4885
US-20260107628-A1 SYNTHESIS METHOD FOR HEXAPHENYLBENZENE-BASED ORGANIC SMALL MOLECULES AND APPLICATION IN ELECTROLUMINESCENT DEVICES TYR, DDT, DDB1 NR1H4 3463/4885EPHX2 3294/4885ESRRB 3123/4885
US-20220081378-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CCNL2, ORC3, OR51E2 NR1H4 800/4885EPHX2 2407/4885ESRRB 609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.