Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660943 | 0.76 | EZH2 (0.33) | EZH2 | |
| SCHEMBL661004 | 0.70 | EZH2 (0.36) | EZH2 | |
| SCHEMBL659536 | 0.69 | EZH2 (0.31) | EZH2 | |
| SCHEMBL9027839 | 0.69 | PTGS1 (0.33) | EZH2 | |
| SCHEMBL659615 | 0.69 | EZH2 (0.31) | EZH2 | |
| SCHEMBL9028069 | 0.69 | ALOX5 (0.33) | EZH2 | |
| SCHEMBL8878018 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL8878076 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL8876889 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL9571390 | 0.67 | EZH2 (0.31) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406243-A1 | BENZOFURAN DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010104194-A1 | BENZOFURAN DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | WO | disclosed |