Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1724213 | 0.88 | GLA (0.33) | FFAR4ALDH1A1HSD17B10GLAHSP90AA1 | |
| SCHEMBL659593 | 0.74 | HTR7 (0.37) | FFAR4ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL658414 | 0.74 | FFAR4 (0.35) | FFAR4ALDH1A1MAPK1MAPTTSHR | |
| SCHEMBL659855 | 0.70 | PIK3CA (0.36) | FFAR4LMNAMAPTALOX15 | |
| SCHEMBL660378 | 0.68 | FFAR4 (0.40) | FFAR4KDM4EALDH1A1MAPK1 | |
| SCHEMBL658001 | 0.68 | HSP90AA1 (0.42) | HTR2BKDM4EALDH1A1LMNAHSP90AA1 | |
| SCHEMBL658842 | 0.67 | HTR1A (0.38) | KDM4EALDH1A1CYP2D6MAPTALOX15 | |
| SCHEMBL660332 | 0.66 | DRD2 (0.39) | FFAR4ALDH1A1LMNA | |
| SCHEMBL659198 | 0.66 | CCR1 (0.42) | LMNAMAPT | |
| SCHEMBL657755 | 0.66 | HSP90AA1 (0.32) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406243-A1 | BENZOFURAN DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010104194-A1 | BENZOFURAN DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | WO | disclosed |