Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.79 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.79 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.79 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.79 |
| ▸ | HTR1A | P08908 | 3/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17242322 | 0.97 | HTR1A (0.76) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17242303 | 0.93 | HTR1A (0.76) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17242096 | 0.92 | HTR1A (0.75) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17242343 | 0.91 | HTR1A (0.73) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17242327 | 0.90 | HTR1A (0.75) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17249509 | 0.90 | HTR1A (0.76) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17242050 | 0.90 | HTR1A (0.74) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17242237 | 0.89 | HTR1A (0.77) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL3377844 | 0.89 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17241849 | 0.88 | HTR1A (0.73) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015169180-A1 | SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-11-12 | — | — | WO | disclosed |
| WO-2015169180-A1 | SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-11-12 | — | — | WO | disclosed |