Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249965 | 0.89 | WNT3A (0.54) | WNT3AWDR5 | |
| SCHEMBL249230 | 0.88 | WNT3A (0.48) | WNT3A | |
| SCHEMBL17243386 | 0.87 | WNT3A (0.46) | WNT3AWDR5 | |
| SCHEMBL249342 | 0.86 | WNT3A (0.66) | WNT3A | |
| SCHEMBL10258040 | 0.85 | WNT3A (0.53) | WNT3AWDR5 | |
| SCHEMBL249160 | 0.85 | WNT3A (0.53) | WNT3AWDR5 | |
| SCHEMBL14802464 | 0.85 | WDR5 (0.48) | WNT3AWDR5 | |
| SCHEMBL247828 | 0.84 | WNT3A (0.51) | WNT3AWDR5 | |
| SCHEMBL248465 | 0.83 | WNT3A (0.53) | WNT3AWDR5 | |
| SCHEMBL247565 | 0.81 | WNT3A (0.62) | WNT3AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181235-B2 | Substituted pyridines for modulating the WNT signaling pathway | NOVARTIS AG (CH) | 2015-11-10 | — | — | US | disclosed |