Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17243786 | 0.83 | MEN1 (0.44) | MEN1KMT2AFKBP1AEPHA2KDR | |
| SCHEMBL17243792 | 0.82 | FKBP1A (0.40) | FKBP1AEPHA2KDREPHB4HCRTR1 | |
| SCHEMBL3180503 | 0.82 | SCD (0.43) | FKBP1AEPHA2KDREPHB4HCRTR1 | |
| SCHEMBL17243790 | 0.81 | FKBP1A (0.35) | FKBP1AHCRTR1SCDHCRTR2 | |
| SCHEMBL17243781 | 0.79 | EPHA2 (0.58) | MEN1KMT2AEPHA2KDREPHB4 | |
| SCHEMBL17243796 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2AFKBP1AEPHA2KDR | |
| SCHEMBL15417979 | 0.78 | FKBP1A (0.41) | MEN1KMT2AFKBP1AEPHA2KDR | |
| SCHEMBL15417963 | 0.78 | SCD (0.42) | MEN1KMT2AFKBP1AEPHA2KDR | |
| SCHEMBL17243774 | 0.78 | ALDH1A1 (0.52) | MEN1KMT2AFKBP1AEPHA2KDR | |
| SCHEMBL17243782 | 0.78 | FKBP1A (0.41) | MEN1KMT2AFKBP1AEPHA2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181229-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-9181229-B2 | Azole derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |