SCHEMBL172439

SCHEMBL172439

COc1ccc(-c2ccc(-c3ccc(C)cc3)c(F)c2F)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.60
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
KMT2A Q03164 1/20 0.50
RELA Q04206 1/20 0.48
ALKBH3 Q96Q83 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MAPT P10636 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ABL1 P00519 1/20 0.44
ABCB1 P08183 1/20 0.44
BCR P11274 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22561016 0.92 CA12 (0.52) ACHERAB9ANPC1KMT2ASMN1; SMN2
SCHEMBL17775109 0.86 ABL1 (0.43) ACHERAB9ANPC1KMT2ASMN1; SMN2
SCHEMBL172423 0.85 ACHE (0.48) ACHERAB9ANPC1KMT2ARELA
SCHEMBL17775112 0.85 ESR2 (0.44) ACHERAB9ANPC1KMT2ASMN1; SMN2
SCHEMBL6712384 0.84 CYP2C19 (0.46) RAB9ANPC1KMT2ARELASMN1; SMN2
SCHEMBL4567631 0.83 ACHE (0.54) ACHERAB9ANPC1KMT2ARELA
SCHEMBL17570168 0.83 ACHE (0.46) ACHE
SCHEMBL14015537 0.82 ABL1 (0.43) SMN1; SMN2ABL1ABCB1BCRCA12
SCHEMBL12672359 0.82 ESR2 (0.67) RAB9ANPC1KMT2ASMN1; SMN2MAPT
SCHEMBL802792 0.82 ACHE (0.42) ACHERAB9ANPC1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-11788009-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-10-17 US disclosed
US-11760931-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-11762241-B2 Device for the regulation of light transmission MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed
US-11702597-B2 Azo dye MERCK PATENT GMBH (DE) 2023-07-18 US disclosed
US-20230150919-A1 Method for Producing Mono-Cross-Coupled Aromatic Compound Having Leaving Group NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-05-18 US disclosed
WO-2021134885-A1 HIGH-CONTRAST NEGATIVE LIQUID CRYSTAL COMPOSITION CONTAINING PHENYLPROPYLTHIOPHENE AND APPLICATION THEREOF 北京八亿时空液晶科技股份有限公司 2021-07-08 WO disclosed
WO-2020229434-A1 METHOD FOR PREPARING A LIQUID CRYSTAL-BASED SWITCHING ELEMENT MERCK PATENT GMBH (DE) 2020-11-19 WO disclosed
WO-2020127141-A1 SWITCHING LAYERS FOR USE IN A SWITCHING ELEMENT MERCK PATENT GMBH (DE) 2020-06-25 WO disclosed
US-7425355-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2008-09-16 US disclosed
US-20080197319-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT (DE) 2008-08-21 US disclosed
US-20080191166-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20080193681-A1 Liquid-Crystal Medium MERCK PATENT GMBH (DE) 2008-08-14 US disclosed
US-20080191167-A1 Liquid-crystalline medium MERCK PATENT GMBH 2008-08-14 US disclosed
US-7371437-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2008-05-13 US disclosed
US-7335403-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2008-02-26 US disclosed
WO-2008009417-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2008-01-24 WO disclosed
US-20070080324-A1 mixture of polar compounds of negative dielectric anisotropy; electro-optical display with active-matrix addressing based on the ECB(electrically controlled birefringence), PALC (positive charge assisted leakage current) or IPS ( in plane switching) effect MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070051920-A1 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150919-A1 Method for Producing Mono-Cross-Coupled Aromatic Compound Having Leaving Group DDC, PAH, ATIC ACHE 2454/4885RAB9A 2875/4885NPC1 2885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.