Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431710 | 0.86 | ALDH1A1 (0.44) | L3MBTL1NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL2431713 | 0.86 | ALDH1A1 (0.44) | L3MBTL1NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL5446807 | 0.81 | ABCC1 (0.34) | LMNANPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL5446806 | 0.81 | ABCC1 (0.34) | LMNANPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6103454 | 0.79 | ALDH1A1 (0.33) | L3MBTL1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4346529 | 0.79 | HTT (0.39) | LMNANR1I2CYP2E1AXLALDH1A1 | |
| SCHEMBL12949686 | 0.79 | NR1I2 (0.39) | LMNANR1I2CYP2E1AXLL3MBTL1 | |
| SCHEMBL4346533 | 0.79 | HTT (0.39) | LMNANR1I2CYP2E1AXLALDH1A1 | |
| SCHEMBL4152499 | 0.79 | NR1I2 (0.38) | NR1I2CYP2E1 | |
| SCHEMBL4152502 | 0.79 | NR1I2 (0.38) | NR1I2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507249-B1 | INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES INC (US) | 2015-11-11 | — | — | EP | disclosed |