Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431710 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1CASP3SENP7 | |
| SCHEMBL2431713 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1CASP3SENP7 | |
| SCHEMBL5731448 | 0.81 | ALDH1A1 (0.33) | ALDH1A1KMT2AMEN1RAB9AGAA | |
| SCHEMBL6102735 | 0.80 | — | — | |
| SCHEMBL17244346 | 0.79 | LMNA (0.35) | ALDH1A1KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL5403025 | 0.75 | KDM4E (0.39) | ALDH1A1KMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL5403021 | 0.75 | KDM4E (0.39) | ALDH1A1KMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL6101904 | 0.75 | IKBKB (0.34) | — | |
| SCHEMBL6102956 | 0.75 | GRM5 (0.37) | KMT2AMEN1CASP3SENP7RAB9A | |
| SCHEMBL5731426 | 0.73 | ALOX5 (0.34) | ALDH1A1KMT2AMEN1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006072347-A2 | ALKINYL-SUBSTITUTED THIOPHENES | AICURIS GMBH & CO. KG (DE) | 2006-07-13 | — | — | WO | disclosed |