Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446806 | 1.00 | ABCC1 (0.34) | ABCC1ABCG2ALDH1A1HPGDKDM4E | |
| SCHEMBL5403025 | 0.86 | KDM4E (0.39) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL5403021 | 0.86 | KDM4E (0.39) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL5731426 | 0.84 | ALOX5 (0.34) | ALDH1A1HPGDKDM4EGAAKMT2A | |
| SCHEMBL17244346 | 0.81 | LMNA (0.35) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL5731448 | 0.78 | ALDH1A1 (0.33) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL5446830 | 0.78 | MDM2 (0.33) | MAPK1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL5446834 | 0.78 | MDM2 (0.33) | MAPK1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL5434896 | 0.76 | RAB9A (0.42) | ABCC1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL5434891 | 0.76 | RAB9A (0.42) | ABCC1ALDH1A1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099929-A1 | Substituted thiophenes | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099929-A1 | Substituted thiophenes | TPMT, HAVCR2, MTAP | ABCC1 765/4885ABCG2 93/4885ALDH1A1 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.