SCHEMBL17244591

SCHEMBL17244591

CCc1nc(-c2ccccc2)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
LMNA P02545 3/20 0.38
HTT P42858 2/20 0.37
NPC1 O15118 1/20 0.37
MAPT P10636 1/20 0.37
XBP1 P17861 1/20 0.37
RAB9A P51151 1/20 0.37
PAX8 Q06710 1/20 0.37
ATM Q13315 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
PDE4B Q07343 5/20 0.36
PDE4D Q08499 4/20 0.36
ADORA2A P29274 2/20 0.36
ADORA1 P30542 2/20 0.36
ACP1 P24666 1/20 0.36
POLB P06746 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
ADORA2B P29275 1/20 0.36
CCNB2 O95067 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12952424 0.85 LMNA (0.39) L3MBTL1LMNAHTTNPC1MAPT
SCHEMBL11978708 0.82 L3MBTL1 (0.58) L3MBTL1LMNAHTTNPC1MAPT
SCHEMBL28827877 0.82 L3MBTL1 (0.52) L3MBTL1LMNAHTTNPC1MAPT
SCHEMBL4900598 0.82 MEN1 (0.47) L3MBTL1LMNAHTTNPC1MAPT
SCHEMBL80527 0.82 MEN1 (0.47) L3MBTL1LMNAHTTNPC1MAPT
SCHEMBL23775950 0.78 L3MBTL1 (0.54) L3MBTL1LMNANPC1MAPTRAB9A
SCHEMBL125466 0.78 MEN1 (0.44) L3MBTL1LMNAHTTNPC1MAPT
SCHEMBL9079576 0.77 L3MBTL1 (0.64) L3MBTL1LMNAHTTNPC1MAPT
SCHEMBL7523521 0.77 LMNA (0.44) L3MBTL1LMNAHTTNPC1MAPT
SCHEMBL18595393 0.77 L3MBTL1 (0.40) L3MBTL1NPC1MAPTRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1471387-B1 Photosensitive composition and compound used thereof FUJIFILM CORP (JP) 2015-11-11 EP disclosed