Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17245245 | 0.93 | KMT2A (0.39) | L3MBTL1SCN9A | |
| SCHEMBL17245232 | 0.91 | CCR2 (0.35) | CCR2SCN9A | |
| SCHEMBL17245224 | 0.91 | KMT2A (0.40) | CCR2L3MBTL1SCN9A | |
| SCHEMBL17428266 | 0.89 | GAA (0.35) | EPHX2CCR2NR1H4NAAASCN9A | |
| SCHEMBL17245221 | 0.87 | CCR2 (0.35) | CCR2L3MBTL1NAAASCN9A | |
| SCHEMBL17245219 | 0.86 | CCR2 (0.34) | CCR2L3MBTL1NAAA | |
| SCHEMBL17251664 | 0.85 | SCN9A (0.32) | SCN9A | |
| SCHEMBL17245240 | 0.85 | SCN9A (0.38) | L3MBTL1NAAASCN9A | |
| SCHEMBL17245217 | 0.84 | KMT2A (0.45) | L3MBTL1NAAASCN9A | |
| SCHEMBL17245242 | 0.82 | KMT2A (0.41) | L3MBTL1NAAASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700047-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-9700047-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-03-02 | — | — | US | disclosed |
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-03-02 | — | — | US | disclosed |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-11-12 | — | — | US | disclosed |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-11-12 | — | — | US | disclosed |
| WO-2015171408-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, CYP4F2 | EPHX2 1111/4885CCR2 4081/4885NR1H4 1775/4885 |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | EPHX2 1246/4885CCR2 3889/4885NR1H4 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.