Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17245224 | 0.93 | KMT2A (0.40) | CCR2SCN9A | |
| SCHEMBL17245242 | 0.91 | KMT2A (0.41) | SCN9A | |
| SCHEMBL17245243 | 0.91 | EPHX2 (0.34) | CCR2SCN9A | |
| SCHEMBL17245221 | 0.89 | CCR2 (0.35) | CCR2SCN9A | |
| SCHEMBL17428275 | 0.89 | GAA (0.36) | CCR2RORCSCN9A | |
| SCHEMBL17245219 | 0.88 | CCR2 (0.34) | CCR2 | |
| SCHEMBL17245235 | 0.88 | KMT2A (0.34) | SCN9A | |
| SCHEMBL18403246 | 0.86 | KMT2A (0.36) | SCN9A | |
| SCHEMBL16865249 | 0.86 | KMT2A (0.36) | SCN9A | |
| SCHEMBL17245217 | 0.86 | KMT2A (0.45) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700047-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-9700047-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-03-02 | — | — | US | disclosed |
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-03-02 | — | — | US | disclosed |
| WO-2015171408-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-11-12 | — | — | WO | disclosed |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-11-12 | — | — | US | disclosed |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170055528-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, CYP4F2 | CCR2 4081/4885RORC 822/4885SCN9A 1707/4885 |
| US-20150322051-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | CCR2 3889/4885RORC 1005/4885SCN9A 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.