Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173553 | 0.81 | PDE2A (0.47) | PDE2APDE10ACYP1A2GRM8GRM7 | |
| SCHEMBL158125 | 0.80 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL22609776 | 0.69 | PTGS2 (0.40) | ALDH1A1CYP2C19 | |
| SCHEMBL21342460 | 0.68 | KMT2A (0.44) | KDM4EALDH1A1HPGD | |
| SCHEMBL671210 | 0.67 | PTPN11 (0.37) | MAPT | |
| SCHEMBL1725188 | 0.66 | MAPT (0.49) | POLBMAPK14MAPTALDH1A1 | |
| SCHEMBL173584 | 0.66 | PDE10A (0.47) | PDE2APDE10ACYP1A2GRM8GRM7 | |
| SCHEMBL17674744 | 0.65 | MAPK14 (0.50) | PDE2APDE10ACYP1A2GRM8GRM7 | |
| SCHEMBL22609734 | 0.64 | AKR1C3 (0.36) | MAPTKDM4EALDH1A1 | |
| SCHEMBL1724913 | 0.63 | PDE2A (0.41) | PDE2APDE10ACYP1A2GRM8GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403834-A1 | Fungicidal pyrazoles | E. I. du Pont de Nemours and Company (US) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010101973-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-10 | — | — | WO | disclosed |