Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173619 | 0.81 | HSD11B1 (0.47) | PTPN11SCN10AP2RX7HSD11B1MAPT | |
| SCHEMBL29520229 | 0.81 | HSD11B1 (0.47) | PTPN11SCN10AP2RX7HSD11B1MAPT | |
| SCHEMBL157185 | 0.78 | MDM2 (0.41) | NR3C2NR3C1 | |
| SCHEMBL30211225 | 0.78 | MDM2 (0.41) | NR3C2NR3C1 | |
| SCHEMBL1726063 | 0.71 | HSD11B1 (0.40) | PTPN11SCN10AP2RX7HSD11B1CYP3A4 | |
| SCHEMBL23804418 | 0.71 | EGLN2 (0.43) | MAPTCYP3A4AR | |
| SCHEMBL17514923 | 0.69 | HSD11B1 (0.47) | PTPN11SCN10AP2RX7HSD11B1NR3C2 | |
| SCHEMBL20698175 | 0.69 | HSD11B1 (0.49) | PTPN11P2RX7HSD11B1 | |
| SCHEMBL20698256 | 0.69 | MAPT (0.49) | HSD11B1MAP3K14MAPTCYP3A4 | |
| SCHEMBL1725607 | 0.69 | MAPT (0.49) | NR3C2MAPTSLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024586-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-23 | — | — | WO | disclosed |