SCHEMBL17248252

SCHEMBL17248252

c1ccc(-c2cc(-n3c4ccccc4c4ccccc43)nc(-n3c4ccccc4c4c3ccc3c5ccccc5n(-c5ccccc5)c34)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.38
KDM4E B2RXH2 2/20 0.38
ATM Q13315 1/20 0.38
KMT2A Q03164 2/20 0.32
IL1R1 P14778 1/20 0.32
MAPT P10636 3/20 0.31
MAPK1 P28482 3/20 0.31
ALDH1A1 P00352 2/20 0.31
HTT P42858 2/20 0.31
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
ACHE P22303 1/20 0.30
PIK3CA P42336 1/20 0.30
HPGD P15428 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16451807 0.95 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL16451924 0.93 MAPT (0.32) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL12131958 0.93 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21017500 0.91 L3MBTL1 (0.39) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17248251 0.91 L3MBTL1 (0.40) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15625697 0.91 L3MBTL1 (0.40) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17248263 0.91 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL2741466 0.91 KDM4E (0.44) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL24163793 0.91 KDM4E (0.34) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL17248256 0.90 MAPT (0.41) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361378-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-23 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10361378-B2 Organic electroluminescent device ELF3, DDT, LEF1 L3MBTL1 74/4885KDM4E 1228/4885ATM 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.