SCHEMBL1724850

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1722249	0.93	ROCK2 (0.87)	ROCK2ROCK1AURKBPRKD3CSNK2A1
	SCHEMBL877371	0.90	ROCK2 (1.00)	ROCK2ROCK1AURKBPRKD3CSNK2A1
	SCHEMBL13186781	0.90	ROCK2 (0.81)	ROCK2ROCK1AURKBPRKD3CSNK2A1
	Trifluoroacetic Acid SCHEMBL1723799	0.89	ROCK2 (0.81)	ROCK2ROCK1AURKBPRKD3CSNK2A1
	SCHEMBL1727178	0.89	ROCK2 (0.81)	ROCK2ROCK1AURKBPRKD3CSNK2A1
	SCHEMBL877349	0.87	ROCK2 (0.84)	ROCK2ROCK1AURKBPRKD3CSNK2A1
	SCHEMBL3790306	0.87	ROCK2 (0.77)	ROCK2ROCK1AURKBPRKD3CSNK2A1
	SCHEMBL877053	0.86	ROCK2 (0.76)	ROCK2ROCK1AURKBPRKD3CSNK2A1
	SCHEMBL21136953	0.86	ROCK2 (0.76)	ROCK2ROCK1AURKBPRKD3CSNK2A1
	Hydrochloric Acid SCHEMBL877107	0.86	ROCK2 (0.83)	ROCK2ROCK1AURKBPRKD3CSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.