Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL612389 | 0.99 | NAAA (0.42) | NAAAPLATGPR119MAPTMAPK14 | |
| SCHEMBL3783681 | 0.81 | GPR119 (0.54) | NAAAGPR119MAPTALDH1A1KMT2A | |
| SCHEMBL13186625 | 0.81 | NAAA (0.42) | NAAAGPR119MAPTMAPK1TSHR | |
| SCHEMBL4528547 | 0.78 | GPR119 (0.58) | NAAAGPR119MAPTTSHRMEN1 | |
| SCHEMBL610359 | 0.77 | GPR119 (0.54) | NAAAGPR119MAPK1ALDH1A1KMT2A | |
| SCHEMBL608951 | 0.77 | GPR119 (0.72) | GPR119ALDH1A1 | |
| SCHEMBL14640643 | 0.75 | GPR119 (0.48) | NAAAPLATGPR119MAPTTSHR | |
| SCHEMBL14640645 | 0.75 | NAAA (0.44) | NAAAPLATGPR119MAPTMAPK1 | |
| SCHEMBL14640814 | 0.70 | GPR119 (0.41) | NAAAPLATGPR119MAPTMAPK1 | |
| SCHEMBL14640819 | 0.70 | GPR119 (0.54) | NAAAPLATGPR119MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406256-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103335-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |