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Sugi Predict / Compounds / SCHEMBL172497

SCHEMBL172497

SCHEMBL172497

C=CC(=O)OCc1ccc(N(c2ccc(OC(=O)C=C)cc2)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 3/20 0.48
▸ PDE6D O43924 1/20 0.42
▸ FFAR1 O14842 1/20 0.41
▸ PTGES O14684 1/20 0.41
▸ ALOX5 P09917 1/20 0.41
▸ HCAR2 Q8TDS4 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ LMNA P02545 1/20 0.39
▸ EPHX1 P07099 1/20 0.38
▸ ENPP2 Q13822 1/20 0.38
▸ ASAH1 Q13510 1/20 0.38
▸ PPARG P37231 3/20 0.37
▸ PPARA Q07869 3/20 0.37
▸ GSTP1 P09211 1/20 0.37
▸ NAAA Q02083 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11987076 0.94 THRB (0.51) THRBPDE6DHCAR2NPC1RAB9A
SCHEMBL13778858 0.94 HCAR2 (0.45) THRBFFAR1PTGESALOX5HCAR2
SCHEMBL172480 0.94 HCAR2 (0.45) THRBFFAR1PTGESALOX5HCAR2
SCHEMBL9915733 0.92 HCAR2 (0.44) THRBFFAR1PTGESALOX5HCAR2
SCHEMBL16625920 0.91 HCAR2 (0.45) THRBHCAR2NPC1RAB9ALMNA
SCHEMBL13777455 0.91 HCAR2 (0.45) THRBHCAR2NPC1RAB9ALMNA
SCHEMBL12534114 0.91 HCAR2 (0.45) THRBHCAR2NPC1RAB9ALMNA
SCHEMBL16625916 0.91 HCAR2 (0.45) THRBHCAR2NPC1RAB9ALMNA
SCHEMBL2602538 0.91 THRB (0.56) THRBPDE6DHCAR2NPC1LMNA
SCHEMBL172586 0.90 THRB (0.48) THRBPDE6DFFAR1HCAR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 — — US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 — — US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 — — US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 — — US disclosed
US-8247143-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2012-08-21 — — US disclosed
US-8247143-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2012-08-21 — — US disclosed
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 — — EP disclosed
US-8043773-B2 surface layer having a good anti-abrasion property, good electric characteristics and a good cleaning property for a spherical toner; photosensitive layer on an electroconductive substrate; Particulates having a needle form are dispersed in the surface layer of the photosensitive layer RICOH COMPANY, LIMITED (JP) 2011-10-25 — — US disclosed
US-8043773-B2 surface layer having a good anti-abrasion property, good electric characteristics and a good cleaning property for a spherical toner; photosensitive layer on an electroconductive substrate; Particulates having a needle form are dispersed in the surface layer of the photosensitive layer RICOH COMPANY, LIMITED (JP) 2011-10-25 — — US disclosed
US-7985520-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2011-07-26 — — US disclosed
US-20080318142-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR PREPARING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD AND APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-12-25 — — US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 — — US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 — — US disclosed
US-20080241716-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-10-02 — — US disclosed
US-20080241716-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-10-02 — — US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 — — US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 — — US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 — — US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 — — US disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 — — EP disclosed