Sugi Predict

Sugi Predict / Compounds / SCHEMBL172586

SCHEMBL172586

SCHEMBL172586

C=CC(=O)OCc1ccc(N(c2ccc(OC(=O)C=C)cc2)c2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 3/20 0.48
▸ NR3C1 P04150 1/20 0.42
▸ LTA4H P09960 1/20 0.42
▸ MMP2 P08253 1/20 0.42
▸ FFAR1 O14842 3/20 0.41
▸ FFAR4 Q5NUL3 1/20 0.41
▸ TGM2 P21980 2/20 0.41
▸ HCAR2 Q8TDS4 1/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ F13A1 P00488 1/20 0.40
▸ TGM1 P22735 1/20 0.40
▸ SRD5A2 P31213 2/20 0.40
▸ PPARG P37231 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ PDE6D O43924 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172457 0.96 THRB (0.48) THRBNR3C1LTA4HMMP2FFAR1
SCHEMBL11987076 0.94 THRB (0.51) THRBTGM2HCAR2SMN1; SMN2LMNA
SCHEMBL2602538 0.91 THRB (0.56) THRBHCAR2SMN1; SMN2LMNAPDE6D
SCHEMBL172497 0.90 THRB (0.48) THRBFFAR1HCAR2PPARGLMNA
SCHEMBL11987088 0.90 ELANE (0.43) THRBNR3C1LTA4HMMP2FFAR1
SCHEMBL11987094 0.89 THRB (0.45) THRBNR3C1LTA4HMMP2FFAR1
SCHEMBL2429423 0.88 THRB (0.55) THRBLTA4HMMP2FFAR1FFAR4
SCHEMBL9915807 0.88 TGM2 (0.50) THRBNR3C1LTA4HTGM2SMN1; SMN2
SCHEMBL11987104 0.87 THRB (0.40) THRBNR3C1LTA4HMMP2FFAR1
SCHEMBL2602487 0.87 HCAR2 (0.49) THRBTGM2HCAR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 — — US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 — — US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 — — US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 — — US disclosed
US-8247143-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2012-08-21 — — US disclosed
US-8247143-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2012-08-21 — — US disclosed
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 — — EP disclosed
US-8043773-B2 surface layer having a good anti-abrasion property, good electric characteristics and a good cleaning property for a spherical toner; photosensitive layer on an electroconductive substrate; Particulates having a needle form are dispersed in the surface layer of the photosensitive layer RICOH COMPANY, LIMITED (JP) 2011-10-25 — — US disclosed
US-8043773-B2 surface layer having a good anti-abrasion property, good electric characteristics and a good cleaning property for a spherical toner; photosensitive layer on an electroconductive substrate; Particulates having a needle form are dispersed in the surface layer of the photosensitive layer RICOH COMPANY, LIMITED (JP) 2011-10-25 — — US disclosed
US-7985520-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2011-07-26 — — US disclosed
US-20080318142-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR PREPARING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD AND APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-12-25 — — US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 — — US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 — — US disclosed
US-20080241716-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-10-02 — — US disclosed
US-20080241716-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-10-02 — — US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 — — US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 — — US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 — — US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 — — US disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 — — EP disclosed