SCHEMBL17249757

SCHEMBL17249757

Cc1ccc(S(=O)(=O)CCCC(C)(C)C)cc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
CYP2C19 P33261 2/20 0.71
CYP3A4 P08684 1/20 0.71
CYP2C9 P11712 1/20 0.71
KMT2A Q03164 6/20 0.53
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.47
MCHR1 Q99705 1/20 0.45
CA2 P00918 1/20 0.45
LMNA P02545 2/20 0.44
MAPT P10636 1/20 0.44
GAA P10253 1/20 0.43
PAX8 Q06710 1/20 0.43
CTSK P43235 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
G6PD P11413 1/20 0.42
MMP8 P22894 1/20 0.41
MMP13 P45452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11778795 0.93 ALDH1A1 (0.67) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL17803840 0.89 ALDH1A1 (0.64) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL1582969 0.84 ALDH1A1 (0.91) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL1820762 0.84 ALDH1A1 (1.00) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL18856899 0.84 ALDH1A1 (0.69) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL14646692 0.84 PLCG1 (0.52) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL19938034 0.84 GAA (0.53) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL1908884 0.83 PSIP1 (0.52) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL8971703 0.82 ALDH1A1 (0.87) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL5463183 0.82 ALDH1A1 (0.87) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9290623-B2 Composition for forming silicon-containing resist underlayer film having cyclic diester group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-03-22 US disclosed
US-20150322212-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM HAVING CYCLIC DIESTER GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150322212-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM HAVING CYCLIC DIESTER GROUP ASH2L, SRRM2, CCNT1 ALDH1A1 2432/4885CYP2C19 3635/4885CYP3A4 2692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.