Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451016 | 0.88 | PSIP1 (0.56) | PSIP1HSD11B1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL10482034 | 0.85 | CA2 (0.56) | PSIP1HSD11B1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL15803386 | 0.83 | PSIP1 (0.43) | PSIP1HSD11B1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL17249757 | 0.83 | ALDH1A1 (0.71) | ALDH1A1CYP3A4CYP2C9CYP2C19MMP8 | |
| SCHEMBL16788409 | 0.82 | CHRM2 (0.42) | PSIP1HSD11B1KEAP1NFE2L2MAPT | |
| SCHEMBL14646692 | 0.81 | PLCG1 (0.52) | HSD11B1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19938034 | 0.81 | GAA (0.53) | ALDH1A1CYP3A4CYP2C9CYP2C19MMP8 | |
| SCHEMBL576918 | 0.81 | KEAP1 (0.63) | PSIP1HSD11B1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL10629823 | 0.81 | PSIP1 (0.61) | PSIP1HSD11B1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL2831871 | 0.81 | KEAP1 (0.47) | PSIP1HSD11B1KEAP1NFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710199-B | Photooxidation reduction catalytic process | 深圳湾实验室坪山生物医药研发转化中心 | 2024-06-28 | — | — | CN | disclosed |
| EP-4252848-A2 | OXYSTEROLS AND METHODS OF USE THEREOF | Sage Therapeutics, Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3529257-B1 | OXYSTEROLS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS INC (US) | 2023-05-10 | — | — | EP | disclosed |
| CN-115745836-A | Method for inducing reaction of alkyl neopentyl benzene and capture reagent by photocatalyst | 深圳湾实验室坪山生物医药研发转化中心 | 2023-03-07 | — | — | CN | disclosed |
| CN-115710199-A | Photo-oxidation-reduction catalysis method | 深圳湾实验室坪山生物医药研发转化中心 | 2023-02-24 | — | — | CN | disclosed |
| CN-113387837-B | Photo-oxidation-reduction catalysis method | 深圳湾实验室坪山生物医药研发转化中心 | 2023-02-21 | — | — | CN | disclosed |
| CN-113387837-A | Photo-oxidation-reduction catalysis method | 深圳湾实验室坪山生物医药研发转化中心 | 2021-09-14 | — | — | CN | disclosed |
| WO-2018075699-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2018-04-26 | — | — | WO | disclosed |
| US-20170322491-A1 | RESIST UNDERLAYER FILM FORMING COMPOSITION FOR LITHOGRAPHY CONTAINING HYDROLYZABLE SILANE HAVING HALOGEN-CONTAINING CARBOXYLIC ACID AMIDE GROUP | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-11-09 | — | — | US | disclosed |
| US-20170168397-A1 | SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION HAVING HALOGENATED SULFONYLALKYL GROUP | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-06-15 | — | — | US | disclosed |
| US-20170153549-A1 | SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION HAVING ORGANIC GROUP HAVING ALIPHATIC POLYCYCLIC STRUCTURE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-06-01 | — | — | US | disclosed |
| US-9290623-B2 | Composition for forming silicon-containing resist underlayer film having cyclic diester group | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-03-22 | — | — | US | disclosed |
| US-20150322212-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM HAVING CYCLIC DIESTER GROUP | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| US-8324239-B2 | Furopyridine compounds and uses thereof | NOVARTIS AG (CH) | 2012-12-04 | — | — | US | disclosed |
| US-20120015907-A1 | Furopyridine compounds and uses thereof | NOVARTIS AG (CH) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322212-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM HAVING CYCLIC DIESTER GROUP | ASH2L, SRRM2, CCNT1 | PSIP1 2380/4885HSD11B1 546/4885KEAP1 4353/4885 |
| US-20120015907-A1 | Furopyridine compounds and uses thereof | CYP3A5, QDPR, DPYD | PSIP1 1432/4885HSD11B1 1902/4885KEAP1 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.