Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.67 |
| ▸ | HTR1D | P28221 | 1/20 | 0.64 |
| ▸ | HTR1B | P28222 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468393 | 1.00 | HTR1A (0.67) | HTR1AHTR1DHTR1BDRD2HTR2A | |
| SCHEMBL3094934 | 0.96 | HTR1A (0.68) | HTR1A | |
| SCHEMBL11358662 | 0.93 | HTR1A (0.60) | HTR1ADRD2HTR2A | |
| SCHEMBL7956463 | 0.86 | HTR1A (0.77) | HTR1A | |
| SCHEMBL8335869 | 0.86 | HTR1A (0.67) | HTR1ADRD2HTR2A | |
| SCHEMBL27336161 | 0.86 | HTR1A (0.67) | HTR1A | |
| Tert-Butyl Formate SCHEMBL27941379 | 0.85 | HTR1A (0.59) | HTR1A | |
| SCHEMBL15586371 | 0.85 | HTR1A (0.68) | HTR1A | |
| SCHEMBL8557189 | 0.84 | HTR6 (0.64) | HTR1A | |
| SCHEMBL26509271 | 0.84 | SLC6A4 (0.63) | HTR1AHTR1DHTR1BDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511173-B | Indole alkyl piperazine benzamide compound and application thereof | 复旦大学 | 2023-06-23 | — | — | CN | disclosed |
| WO-2015169180-A1 | SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-11-12 | — | — | WO | disclosed |