Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.48 |
| ▸ | ACACB | O00763 | 3/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475741 | 0.66 | ACACB (0.86) | MTNR1AACACB | |
| SCHEMBL126690 | 0.65 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL25100769 | 0.65 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL16938261 | 0.64 | KDM4E (0.42) | — | |
| SCHEMBL12001427 | 0.63 | ACACB (0.79) | MTNR1AACACB | |
| SCHEMBL14976630 | 0.63 | KMT2A (0.63) | ACACB | |
| SCHEMBL23099061 | 0.62 | PRMT5 (0.45) | — | |
| SCHEMBL13724706 | 0.62 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8569058 | 0.61 | MTNR1A (0.79) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL255805 | 0.61 | ACACB (1.00) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100895-B1 | TRICYCLIC COMPOUND AND MEDICAL USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-03-07 | — | — | EP | disclosed |