Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.78 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.78 |
| ▸ | NQO2 | P16083 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SPR | P35270 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144427 | 0.88 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2KMT2ASPR | |
| SCHEMBL31543637 | 0.81 | SPR (0.73) | MTNR1AMTNR1BNQO2SPRHDAC3 | |
| SCHEMBL31543647 | 0.81 | SPR (0.73) | MTNR1AMTNR1BNQO2SPRHDAC3 | |
| SCHEMBL21614281 | 0.81 | ADRB2 (0.55) | MTNR1AMTNR1BNQO2KMT2ASPR | |
| SCHEMBL8143092 | 0.80 | MTNR1A (0.81) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL20307238 | 0.79 | HDAC3 (0.58) | MTNR1AMTNR1BNQO2HDAC3HDAC6 | |
| SCHEMBL12720755 | 0.79 | SPR (0.69) | MTNR1AMTNR1BNQO2KMT2ASPR | |
| SCHEMBL8712203 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6761760 | 0.78 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2KMT2ASPR | |
| SCHEMBL4509981 | 0.77 | NQO2 (0.64) | MTNR1AMTNR1BNQO2KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |