Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL857211 | 0.82 | FGFR1 (0.43) | FGFR1FGFR4ENPP3ENPP1HSD17B10 | |
| SCHEMBL22130207 | 0.81 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL17253109 | 0.81 | DGAT1 (0.37) | FGFR1FGFR4DGAT1 | |
| SCHEMBL14136876 | 0.78 | FGFR1 (0.46) | FGFR1FGFR4ENPP3ENPP1HSD17B10 | |
| SCHEMBL31126947 | 0.76 | FGFR1 (0.44) | FGFR1FGFR4ENPP3ENPP1HSD17B10 | |
| SCHEMBL23926476 | 0.76 | ALDH1A1 (0.42) | ENPP3ENPP1DGAT1MAOB | |
| SCHEMBL15712213 | 0.74 | FGFR1 (0.50) | FGFR1FGFR4ENPP3ENPP1HDAC8 | |
| SCHEMBL7859822 | 0.74 | HTR7 (0.42) | FGFR1FGFR4ENPP3ENPP1 | |
| SCHEMBL20985874 | 0.73 | FGFR1 (0.42) | FGFR1FGFR4ENPP3ENPP1HSD17B10 | |
| SCHEMBL3560778 | 0.73 | FGFR1 (0.42) | FGFR1FGFR4ENPP3ENPP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015170775-A1 | SUBSTITUTED AZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES | 日産化学工業株式会社 | 2015-11-12 | — | — | WO | disclosed |