Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292009 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TDP1GAATSHRRAB9A | |
| SCHEMBL18622524 | 0.81 | PPARD (0.51) | ALDH1A1TDP1PPARDPPARAGAA | |
| SCHEMBL3291950 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TDP1PPARDPPARARAB9A | |
| SCHEMBL3291946 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TDP1PPARDPPARARAB9A | |
| SCHEMBL17694527 | 0.79 | RAB9A (0.44) | TDP1PPARDPPARAGAATSHR | |
| SCHEMBL3292480 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1PPARDPPARARAB9A | |
| SCHEMBL8021350 | 0.76 | ALDH1A1 (0.78) | ALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL27263883 | 0.75 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL11844391 | 0.75 | GAA (0.51) | TDP1GAATSHRRAB9ACTBP2 | |
| SCHEMBL17283451 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TDP1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073452-A1 | POLYGLYOXYLATES, MANUFACTURE AND USE THEREOF | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2017-03-16 | — | — | US | disclosed |
| WO-2015168809-A1 | POLYGLYOXYLATES, MANUFACTURE AND USE THEREOF | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2015-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073452-A1 | POLYGLYOXYLATES, MANUFACTURE AND USE THEREOF | IDUA, IDE, PUF60 | ALDH1A1 4449/4885TDP1 606/4885PPARD 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.